Left-of clues: Showing two different tiles with an ellipsis (...) in between, these clues indicate that the first tile is positioned in a column somewhere to the left of the second (although, again, not necessarily adjacent to it). For example, 3...2 tells you that the 3 tile is somewhere to the left of the 2 tile.

Next-to clues: Consisting of one tile in between two of another tile, these clues tell you that the two tiles are in adjacent columns, but it doesn't indicate which is to the right or left of the other. For example, 3E3 means that the letter tile E and the number tile 3 are in columns directly next to each other.

Same-column clues: Showing two different tiles with an up/down arrow in between, these clues reveal tiles that must appear in the same column. For example, 4[arrow]C means that the 4 and C tiles are directly below/above each other.

Guess Again: Use the clues in Marple to eliminating possible tile values.

You use these clues and some clever logic first to eliminate possible tile values, and then to determine which tiles go where. For example, because the middle tile in an in-between clue must be positioned between two other tiles, it can't appear in the left-most (first) or right-most (fifth) column. You can similarly use left-of and same-column clues to narrow down the possibilities for each group of tiles, making the in-between and next-to clues more meaningful. Clues can be dragged to reposition them; for example, to put clues relating to a similar tile together. And if you no longer need a clue, you can tap it to dim it (another tap undims it). This may sound complicated, but you get the hang of it after a few games. And if you get stuck, the developer provides some tips for beginners in the game's excellent Help screen, and a Hint button highlights the clue that will be the most helpful at that moment.