Other speakers include Larry Brilliant, the executive director of , the search-engine giant's philanthropic arm, and Shai Agassi, the former SAP president of products and technology who founded and heads electric-car company .

Also on hand will be Edgar Bronfman, the CEO of Warner Music, who will share the stage with MySpace's DeWolfe to talk about the music industry's future.

New York Magazine's contributing editor, John Heilemann, will moderate a panel about the Web and politics with participants including Arianna Huffington from The Huffington Post and San Francisco Mayor Gavin Newsom.

There will also be panels about technology hot topics such as cloud computing, SaaS, Web application development platforms and mobile Internet services.

As in previous years, John Battelle, chairman of Federated Media Publishing, will act as program chair and interview most of the keynote speakers on stage.