Microsoft applauded the EU antitrust watchdog's decision.

"This is an important milestone, as we've now received clearance from both the United States and the European Union," said Brad Smith, Microsoft's lead lawyer, in a Friday statement. "We look forward to completing soon the final steps needed to close the acquisition."

In June, U.S. regulators at the Department of Justice after also deciding that there was sufficient competition from other major players, including Google.

The Commission's decision stymies a complaint submitted by Messagenet, an Italian rival to Skype, which last month asked regulators to block the deal unless Microsoft agreed not to bundle Skype with its Office products.

Lync, formerly Microsoft Office Communicator, is composed of both server and client pieces, and is under the general Office umbrella.