Instagrille is an interesting mashup between a desktop app and a Web app, and runs in its own window, using a free platform called . It won't let you post new photos to Instagram, but you can browse popular photos, nearby photos, and your timeline (if you log in). You can click on a photo to see a larger version of it, too.
Logged on, you can do most things you can do on your phone: Follow users, Like photos (by double-clicking them, just like double-tapping on the phone), comment on photos, and share them on Facebook and Twitter. Clicking the Share buttons pops up Twitter or Facebook in a built-in dialog, which you then use to share the Instagram link. Instagrille also lets you save individual images to your hard drive as 612 by 612 pixels-large PNG files. The notable omission is posting new photos, something Instagrille does not let you do.
Instagrille offers a fun and compelling way to enjoy your Instagram feed without reaching for a smartphone. If you're constantly draining your phone's battery oohing and aahing at your friends' beautiful photos, Instagrille can be a nice way to view that virtual art gallery on a bigger monitor.
Note: The Download button takes you to the vendor's site, where you can download the latest version of the software.