-- Does the backup system provide complete coverage, including bare-metal support?
-- What agents, additional software or servers do you need to implement the backup product on your systems?
-- Can you exclude and include specific files to be backed up or protected?
Don't forget to protect the data on your handheld device or cell phone using vendor-supplied and third-party utilities. When traveling, use a tiered approach: Back up your handheld to your laptop or a USB device, then back up or replicate the changes on your laptop to a network file or backup server when available.
If you already have a good backup regime, look to see how you can improve it to protect more data in a shorter amount of time. If you do not have a regular backup regime, now is the time to start.