Under the agreement, HP will modernise the trust's technology to enable its workforce to work more flexibly and effectively, enabling it to deliver improved mental and physical healthcare in both inpatient and community services, said the trust.
The trust serves around 800,000 people across North London, and believes the HP deal will help it deliver healthcare services "nearer to those that need it".
HP Enterprise Services will deliver a range of outsourced services to support a fully managed desktop, including application hosting, network management, data centre services and remote support services.
The trust already uses HP servers, storage and networking, and is now the first trust in the UK to take advantage of services through the government's Buying Solutions Desktop21 framework agreement.
This framework aims to provide the NHS and other government bodies with a simplified approach to procurement of desktop and related services as well as saving them money.