Using a traditional PC loaded with Windows 8 promises to be a radically different user experience, especially when it comes to navigating the new OS. Traditional interface elements such as the Start button have been eliminated, and Microsoft has introduced new navigation features such as the right-side charms bar for accessing system features including the Control Panel and system search.
Windows 8 still allows you to use a traditional non-touch enabled mouse. But to navigate the new OS more efficiently you'll probably find it easier to use gestures for at least some situations such as scrolling through Start Screen tiles or switching between the Start Screen and the traditional desktop user interface.
If touch gestures aren't for you, then I would strongly advise you study up on at least some of the . This will help you get around the OS more efficiently without having to worry about relying on Microsoft's somewhat finicky hot corners in Windows 8.